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Side effects of allergy testing?

Question:
I had scratch/prick tests yesterday morning for dozens of allergens (hoping to find out what is contributing to my chronic sinusitis). Everything was negative. Yesterday afternoon I felt like I hit a brick wall -- serious fatigue. I could barely drag myself into the bedroom to go to sleep. I slept almost nine hours last night, and this morning the fatigue continues. It's all I could do to run a couple of errands and drop off my son at camp before coming home and sitting down. I haven't had fatigue like this for months. AND I've been on vacation the last few weeks (lots of good food, sun, rest, naps, sinus problems under control for months, etc.) and have been feeling really great. I'm so discouraged by this, I just started bawling (and I'm not one prone to crying or dramatics). I pulled myself together (crying just makes my sinuses swell, and that's something I want to deal with just now), but I'm pretty sure I'm going to be spending the day in bed. I called the doctor's office, and the nurse/receptionist says there's no way skin testing causes a systemic reaction like fatigue.


Answer:
I believe that most everyone who gives allergy shots has seen many people who have fatigue following their shot. Some will plan to be able to nap after their shot, some will arrange that the shot is followed by a day during which the demands on them are less, and some just find themselves so affected that they are unable to continue. I have not had people tell me of similar reactions after skin testing, but see no reason why such should not occur. I know that doctors are not told of all undesirable rections to treatment, particularly if the symptoms are not feared to be dangerous to life. Many people expect uncomfortable side-effects to all medical procedures, not knowing that they might not be anticipated by the medical personnel in a specific circumstance, and for this reason do not always mention them. It may simply be that such have occurred, but have not been severe enough that they have been reported to me. Lori, usual practice in websites is that answers are given to the group as a whole, as they may interest more than just the original poster and may prompt further valuable discussion. I would point out that the skin tests were negative thus reducing the likelihood of it being a reaction to the test. I think one could reasonably expect a skin reaction if there were a systemic reaction (not mandatory but I think a reasonable first assumption based on the information at hand). I note that she just returned from vacation had the testing then fatigue. That sounds very much like the typical case of someone being out of an exposure area then returning. A couple of questions come to mind. How long after returning from vacation was the testing done? Any over the counter or prescription drugs taken after the tests (asprin, benedryl, decongestants)? Everything was negative - does that mean the histamine control was negative also? And, yes fatigue is a normal side effect of immunotherapy that can occur without much indication of problems at the injection site. I get mine just after work on the way home and plan on crashing for the evening. my answers: I returned from vacation Sunday around 4 p.m. Had a good night's sleep. Felt fine. Went in for allergy testing Monday morning around 10. I'd been off Claritan D since last Wednesday so it wouldn't screw up the test results. Still taking Singulair and Nasonex and the occasional Sudafed (also on Zoloft for an unrelated condition -- no problems with it in several months). Took no medications immediately after the testing. Took Singulair and Zoloft at dinner, after the fatigue had already set in. The cat didn't come home from the vet until late this morning, and she was out of the house a day before we left (time enough to wash and change all linens and clean the house really well -- I hate coming home to a dusty, messy house). And I was actually in the car yesterday when the fatigue first hit, about 4 p.m. (and hadn't been in the house since 8:30 that morning). You're right -- the histamine control was positive. :-) The only other little blip was the breathing test the nurse did before the rest of the stuff -- I never did blow out all the little candles on the computer 'cake' during it. And I had a lot of coughing after. The doctor commented on the amount of it, and said I was probably a 'shallow breather'
(?), but I don't have any experience with breathing tests, so don't know what the significance is. FYI, I am mildly asthmatic -- maybe one or two attacks a year that last an hour or less with use of an albuterol inhaler. I truly do not believe this is trip fatigue. With me, that is usually present immediately after I arrive home and goes away after a night's sleep. The last couple of days of our vacation were pretty low-key, so I actually felt pretty good when we returned home. This evening I'm still fatigued -- not as badly as yesterday afternoon or this morning, but still basically sitting alot and looking forward to bedtime. It was discouraging to have this amount of fatigue. I've been doing pretty well the last couple of months (currently dealing with getting help for chronic sinusitis, the allergy testing being a part of that) and taking care of myself. Vacation was the icing on the cake -- all that resting I got to do was great. And now just two days back, I feel like I've negated all the good that's been done in the last several weeks. Haven't felt this tired in about six months. Based on the other symptomology, not necessarily. I have had an anaphylactic reaction to a patch test with absolutely no redness or swelling at the site. What Lori had could very well be a systemic reaction of less severity. My allergy symptoms often include lethargy and depression, which it sounds like Lori has. It's bad enough that OTC antihistamiines almost always perk me up. While I cannot say for sure that it was the shots causing the reaction (and there is absolutely no way to know which ones did), it sounds suspicious to me.



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